File:Β-Globin-LCR-and-Intron-Elements-Cooperate-and-Direct-Spatial-Reorganization-for-Gene-Therapy-pgen.1000051.s006.ogv

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English: Example 3D DNA FISH reconstruction of transgene localization in uninduced MEL BGT158 cells. The transgene is detected as a red signal by a 10 kb DIG labeled probe using Alexa Fluor 546 labeled tyramide signal amplification with DAPI counterstained nuclear DNA in green. DAPI-rich areas correspond to heterochromatin.
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Source Video S1 from Buzina A, Lo M, Moffett A, Hotta A, Fussner E, Bharadwaj R, Pasceri P, Garcia-Martinez J, Bazett-Jones D, Ellis J (2008). "β-Globin LCR and Intron Elements Cooperate and Direct Spatial Reorganization for Gene Therapy". PLOS Genetics. DOI:10.1371/journal.pgen.1000051. PMID 18404216. PMC: 2271131.
Author Buzina A, Lo M, Moffett A, Hotta A, Fussner E, Bharadwaj R, Pasceri P, Garcia-Martinez J, Bazett-Jones D, Ellis J
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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Date/TimeThumbnailDimensionsUserComment
current21:40, 17 November 201212 s, 1,372 × 954 (1.27 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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