File:12985 2016 561 Fig1A HTML.jpg
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Description12985 2016 561 Fig1A HTML.jpg |
English: Schematic diagram of FMDV genome. FMDV genome RNA contains a single open reading frame (ORF) of about 7 kb with two alternative initiation sites. The ORF is flanked by a long 5ʹ-untranslated region (5ʹ-UTR) and a short 3ʹ-UTR. The 5ʹ-UTR is highly structured and comprises S-fragment, poly(C) tract, 3B-uridylylation site (bus) or cis-acting replication element (cre), pseudoknots (PKs), and internal ribosome entry site (IRES). Protein 3B (VPg) is covalently bound to its 5ʹ end. |
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Source | https://virologyj.biomedcentral.com/articles/10.1186/s12985-016-0561-z |
Author | Yuan Gao, Shi-Qi Sun, and Hui-Chen Guo |
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