File:15010 2020 1486 Fig2 HTML.webp
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Captions
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Receptor-binding domain (RBD) of the S protein may constantly switch between a “lying-down” and a “standing-up” position.
Summary
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| Description |
English: Receptor-binding domain (RBD) of the S protein may constantly switch between a “lying-down” and a “standing-up” position. In SARS-CoV-2, RBD is mostly in the “lying-down” position, a state associated with not only ineffective receptor binding, but also immune evasion. In SARS-CoV, RBD is mostly in “standing-up” position, a state associated with not only high effective receptor binding, but also immune recognition. |
| Date | |
| Source | Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 |
| Author | Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 08:01, 1 February 2021 | | 1,502 × 962 (53 KB) | Guest2625 (talk | contribs) | Uploaded a work by Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla from Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 with UploadWizard |
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