File:A-Helical-Structural-Nucleus-Is-the-Primary-Elongating-Unit-of-Insulin-Amyloid-Fibrils-pbio.0050134.sv002.ogv
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A-Helical-Structural-Nucleus-Is-the-Primary-Elongating-Unit-of-Insulin-Amyloid-Fibrils-pbio.0050134.sv002.ogv (Ogg Theora video file, length 0.0 s, 240 × 240 pixels, 0 bps, file size: 3.1 MB)
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DescriptionA-Helical-Structural-Nucleus-Is-the-Primary-Elongating-Unit-of-Insulin-Amyloid-Fibrils-pbio.0050134.sv002.ogv |
English: Formation of Fibrils from Protofilaments The protofilament is rotated 360° and, subsequently, 90° to show the top view. A second protofilament is shown in the same view. The two protofilaments presumably intertwine to form the protofibril. The view changes after zooming in to show the protofibril surface in orange. The view rotates back 90° and then zooms out. Then the three intertwining protofibrils are shown in orange, red, and yellow, respectively, during two 360° rotations. Following that, four ab initio models of the fibril helical repeat (the coherently scattering unit) are superimposed in grey during four full rotations, changing the view to include or exclude the model of the three intertwining protofibrils. The movie was generated using PyMol (DeLano Scientific, http://www.pymol.org). |
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Source | Video S2 from Vestergaard B, Groenning M, Roessle M, Kastrup J, van de Weert M, Flink J, Frokjaer S, Gajhede M, Svergun D (2007). "A Helical Structural Nucleus Is the Primary Elongating Unit of Insulin Amyloid Fibrils". PLOS Biology. DOI:10.1371/journal.pbio.0050134. PMID 17472440. PMC: 1858711. | ||
Author | Vestergaard B, Groenning M, Roessle M, Kastrup J, van de Weert M, Flink J, Frokjaer S, Gajhede M, Svergun D | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 14:20, 16 November 2012 | 0.0 s, 240 × 240 (3.1 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Formation of Fibrils from Protofilaments |
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Author | Vestergaard B, Groenning M, Roessle M, Kastrup J, van de Weert M, Flink J, Frokjaer S, Gajhede M, Svergun D |
Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2007-05 |