Wikimedia Commons

File:A-MAPK-Driven-Feedback-Loop-Suppresses-Rac-Activity-to-Promote-RhoA-Driven-Cancer-Cell-Invasion-pcbi.1004909.s009.ogv

A-MAPK-Driven-Feedback-Loop-Suppresses-Rac-Activity-to-Promote-RhoA-Driven-Cancer-Cell-Invasion-pcbi.1004909.s009.ogv ‎(Ogg Theora video file, length 2.9 s, 612 × 598 pixels, 4.48 Mbps, file size: 1.53 MB)

Captions

Captions

Add a one-line explanation of what this file represents

Summary edit

Description
English: FRET biosensors reporting Rac1 activity (top) or RhoA activity (bottom) for A2780 cells migrating over a 5 minute timecourse on 3D CDMs, stimulated with cRGDfV and treated with DMSO (left) or MEK1/2 inhibitor PD184352 (right). Thermal look up table applied as in Fig 3E–3H, where red denotes high GTPase activity and green denotes low GTPase activity.
Date
Source S2 Movie from Hetmanski J, Zindy E, Schwartz J, Caswell P (2016). "A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1004909. PMID 27138333. PMC: 4854413.
Author Hetmanski J, Zindy E, Schwartz J, Caswell P
Permission
(Reusing this file)
w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
Provenance
InfoField
This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
WikiProject Open Access
WikiProject Open Access

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current07:10, 18 October 20162.9 s, 612 × 598 (1.53 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

You cannot overwrite this file.

Transcode status

Update transcode status
Format Bitrate Download Status Encode time
VP9 480P 1.4 Mbps Completed 19:46, 15 August 2018 5.0 s
Streaming 480p (VP9) 1.41 Mbps Completed 02:59, 17 December 2023 1.0 s
VP9 360P 711 kbps Completed 19:46, 15 August 2018 5.0 s
Streaming 360p (VP9) 712 kbps Completed 16:33, 17 December 2023 1.0 s
VP9 240P 350 kbps Completed 19:46, 15 August 2018 3.0 s
Streaming 240p (VP9) 351 kbps Completed 04:01, 9 December 2023 1.0 s
WebM 360P 514 kbps Completed 07:10, 18 October 2016 1.0 s
Streaming 144p (MJPEG) 547 kbps Completed 07:34, 29 October 2023 0.0 s

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:A-MAPK-Driven-Feedback-Loop-Suppresses-Rac-Activity-to-Promote-RhoA-Driven-Cancer-Cell-Invasion-pcbi.1004909.s009.ogv&oldid=809456404"