File:Altered-Nucleotide-Microtubule-Coupling-and-Increased-Mechanical-Output-by-a-Kinesin-Mutant-pone.0047148.s003.ogv

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English: NcdY485 residue interactions. The movie shows that Y485 of loop L7 (space-filled, yellow), R552 of switch I (space-filled, purple) and N600 (space-filled, dark green) at the end of switch II helix α4 move and undergo changes in interactions between head H2 of a stalk-rotated Ncd structure (PDB 3L1C) and an unrotated Ncd head (PDB 1CZ7); similar changes in interactions are observed between the two heads, H1 and H2, of the stalk-rotated Ncd structure shown in Figure 1B. Animation made in Chimera [41] using default settings of 20 interpolation steps and 60 minimization steps. Small distortional movements of the central β-sheet (ribbon diagram, pale yellow) can be observed. View from the side of head H2 similar to Figure 1B; head H2 is positioned to bind to the microtubule, while the stalk and H1 rotate towards the microtubule minus end.
Date
Source Movie S1 from Liu H, Hallen M, Endow S (2012). "Altered Nucleotide-Microtubule Coupling and Increased Mechanical Output by a Kinesin Mutant". PLOS ONE. DOI:10.1371/journal.pone.0047148. PMID 23077560. PMC: 3473065.
Author Liu H, Hallen M, Endow S
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Date/TimeThumbnailDimensionsUserComment
current21:33, 9 November 201223 s, 992 × 784 (3.9 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 720P 845 kbps Completed 08:18, 17 August 2018 34 s
Streaming 720p (VP9) 845 kbps Completed 09:43, 25 January 2024 2.0 s
VP9 480P 359 kbps Completed 08:18, 17 August 2018 20 s
Streaming 480p (VP9) 358 kbps Completed 19:58, 17 December 2023 1.0 s
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Streaming 240p (VP9) 104 kbps Completed 00:23, 12 December 2023 1.0 s
WebM 360P 504 kbps Completed 04:19, 16 November 2012 22 s
Streaming 144p (MJPEG) 877 kbps Completed 03:05, 30 October 2023 2.0 s

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