Identifier: archivesofphysic04ameruoft (find matches)
Title: Archives of physical medicine and rehabilitation
Year: 1920 (1920s)
Authors: American Academy of Physical Medicine and Rehabilitation American College of Radiology and Physiotherapy American Congress of Physical Medicine and Rehabilitation Radiological Society of North America
Subjects: Physical therapy
Publisher: (Chicago, etc.)
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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avor of such a belief is enormous, theexperimental evidence obtained on thelower animals is incontrovertible andaccumulating all the time and the prac-tical leadings of such a view are ob-vious. We will now take up some ofthe observations and experimental re-searches which have led to this changeof opinion, and which seem to point toparasites as probable causes. I. TransplantationExperiments We may first consider a few of theresults obtained from transplantationexperiments. Beginning with Jensens brilliantwork on mouse cancer, in 1901-03,workers in many laboratories took upand diligently followed this lead, usingat first his mouse cancer and subse-quently many other forms of cancerfound in mice and rats and other ex-perimental animals, and to such an ex-tent that some cancer laboratories havehad as many as 20,000 mice underobservation at one time and often asmany as several thousand. Jensen wasnot the first to successfully transplant TWENTIETH CEXTURY ADVANCES IN CANCER RESEARCH-SMITH
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!»• .,ul:iliil iwo iiK.nllis (Siniiik f lr2^),. ^ hop strain of Bacterium tumefaclani 296 iv.s boKun To kill the plaitts Inoculations should have been,nad- earlier and centrally. See Plates 2. 3. 4 and J. CancerResearch, l;No. 2. Plates Vll and VII-A. TWENTIETH CENTURY ADVANCES IN CANCER RESEARCH—SMITH cancer. Leo Loebs work on rat thy-roid sarcoma was earlier and therewere others before him, but Jensenswork arrived at the psychological mo-ment, which always means a great deal,and he was able and willing to give hislumor to all who asked for it. These transplantation or grafting ex-periments have taught us many thingsas to the behavior of cancer under agreat variety of controlled conditions,and may teach us much more, especiallyas to therapy, but nothing definite hasbeen learned from them as to etiologyunless il be this that a cancer may beginas a carcinoma and end as a sarcoma.The transplants are to be regarded asartificially produced secondary tumorsand a study of their behavio

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