File:Chimeric-Antigen-Receptor-(CAR)-Specific-Monoclonal-Antibody-to-Detect-CD19-Specific-T-Cells-in-pone.0057838.s010.ogv
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Chimeric-Antigen-Receptor-(CAR)-Specific-Monoclonal-Antibody-to-Detect-CD19-Specific-T-Cells-in-pone.0057838.s010.ogv (Ogg Theora video file, length 48 s, 640 × 480 pixels, 1.02 Mbps, file size: 5.82 MB)
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DescriptionChimeric-Antigen-Receptor-(CAR)-Specific-Monoclonal-Antibody-to-Detect-CD19-Specific-T-Cells-in-pone.0057838.s010.ogv |
English: CAR+ T cells were blocked with Alexa Fluor 647-conjugated clone no. 136.20.1 mAb and co-cultured as described for Movie S1. Movie was made with frames taken at 2 minutes intervals for 11 hours (time on left corner of frame; hr:min:sec) (5 µm scale). Synapse was formed by the effector CAR+ T cell with the Daudi β2m (green fluorescent) target cells, but no lysis of tumor cells occurred even after the tumor and effectors were engaged for more than 6 hours. |
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Source | Movie S2 from Jena B, Maiti S, Huls H, Singh H, Lee D, Champlin R, Cooper L (2013). "Chimeric Antigen Receptor (CAR)-Specific Monoclonal Antibody to Detect CD19-Specific T Cells in Clinical Trials". PLOS ONE. DOI:10.1371/journal.pone.0057838. PMID 23469246. PMC: 3585808. | ||
Author | Jena B, Maiti S, Huls H, Singh H, Lee D, Champlin R, Cooper L | ||
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current | 04:47, 9 March 2013 | 48 s, 640 × 480 (5.82 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Jena B, Maiti S, Huls H, Singh H, Lee D, Champlin R, Cooper L |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2013 |