File:Detection-of-Intra-Tumor-Self-Antigen-Recognition-during-Melanoma-Tumor-Progression-in-Mice-Using-pone.0021214.s009.ogv
Detection-of-Intra-Tumor-Self-Antigen-Recognition-during-Melanoma-Tumor-Progression-in-Mice-Using-pone.0021214.s009.ogv (Ogg Theora video file, length 7.6 s, 644 × 452 pixels, 1.24 Mbps, file size: 1.13 MB)
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DescriptionDetection-of-Intra-Tumor-Self-Antigen-Recognition-during-Melanoma-Tumor-Progression-in-Mice-Using-pone.0021214.s009.ogv |
English: Non-specific OT-1 T cells do not engage in long term interactions with B16 tumor cells. Representative time-lapse image shows close up view of the top middle region from movie S6. YFP-B16 (green) tumor 7 days post transfer of 3×105 naive CD8+ CFP-Pmel-1(Cyan) and CD8+ GFP-OT-1 (red) T cells. Representative T cell tracks are show in red for OT-1 T cells, and blue for Pmel-1 T cells. Density of YFP in the image has been reduced to permit better observation of OT-1 and Pmel-1 T cells. Seventy-seven seconds separate each frame. Arrows (white = Pmel-1, black = OT-1) point to examples of cells which are engaged with tumor cells at the beginning of the movie. Movie demonstrates that non-specific GFP-OT-1 T cells do not engage in long term interactions with tumor cells in contrast to tumor-specific CFP-Pmel-1 T cells. |
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Source | Movie S5 from Schaer D, Li Y, Merghoub T, Rizzuto G, Shemesh A, Cohen A, Li Y, Avogadri F, Toledo-Crow R, Houghton A, Wolchok J (2011). "Detection of Intra-Tumor Self Antigen Recognition during Melanoma Tumor Progression in Mice Using Advanced Multimode Confocal/Two Photon Microscope". PLOS ONE. DOI:10.1371/journal.pone.0021214. PMID 21731676. PMC: 3120835. | ||
Author | Schaer D, Li Y, Merghoub T, Rizzuto G, Shemesh A, Cohen A, Li Y, Avogadri F, Toledo-Crow R, Houghton A, Wolchok J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 12:57, 18 November 2012 | 7.6 s, 644 × 452 (1.13 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Schaer D, Li Y, Merghoub T, Rizzuto G, Shemesh A, Cohen A, Li Y, Avogadri F, Toledo-Crow R, Houghton A, Wolchok J |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2011 |