English: According to the cough respiratory waveforms, we found the amplified sound waveforms. Noise 1 was the sound of head-twtich, the sound was similar to cough. But body movements were shaking head from left to right, which were different from raising head while coughing. Especially, the respiratory waveforms displayed “V” shape which was different from cough ones. Noise 2 was the sound of knocking chamber wall. When moving freely inside the plethysmograph, the mice may make sounds from frequent maneuvers such as nose-scratching, teeth-tapping, sniffing, et al. These sounds and body movements were so different from cough that could be distinguished by manipulator at real time. Otherwise, the noises produced different or no respiratory waveforms, and were thus well differentiated real-time from coughs using the Finepointe software.