File:DyneinDynactin-Mediated-Transport-of-Kinetochore-Components-off-Kinetochores-and-onto-Spindle-Poles-pone.0016494.s008.ogv

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English: NDGA induced accumulation of EGFP-hZW10 by kinetochore ‘shedding’. HeLa cells stably expressing EGFP-hZW10 were treated with 30 µM NDGA and imaged using the spinning disk confocal microscope. Maximum projections of 5 1 µm Z-stacks taken 2.26 seconds apart are shown. EGFP-hZW10 is seen accumulated at the spindle poles at the start of the movie and EGFP-hZW10 foci are seen steaming towards the spindle pole. Time shown as minutes:seconds.milliseconds. Scale bar = 8 µm.
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Source Movie S2 from Famulski J, Vos L, Rattner J, Chan G (2011). "Dynein/Dynactin-Mediated Transport of Kinetochore Components off Kinetochores and onto Spindle Poles Induced by Nordihydroguaiaretic Acid". PLOS ONE. DOI:10.1371/journal.pone.0016494. PMID 21305043. PMC: 3030593.
Author Famulski J, Vos L, Rattner J, Chan G
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current08:27, 14 November 20122.7 s, 606 × 603 (852 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 480P 586 kbps Completed 02:52, 25 August 2018 6.0 s
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