File:Formation and patterning of the mouse neural tube.png

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Description Figure 4. Formation and patterning of the mouse neural tube. (A) The pseudostratified columnar epithelium of neural plate forms by 7.5 dpc. The lateral edges of the neural plate then (B) elevate and (C) fold by ~8.0 dpc before (D) converging at the midline and closing by ~8.5 dpc. Shh (red arrows) and BMP inhibitors secreted from the floor plate, and BMP4/7 (green arrows) secreted from the roof plate act to pattern the neural tube along its ventro-dorsal axis, giving rise to the layers of the spinal cord (Gilbert, 2006). Key: V, ventral; D, dorsal; L, left; R, right.
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Source https://www.researchgate.net/figure/Formation-and-patterning-of-the-mouse-neural-tube-A-The-pseudostratified-columnar_fig3_334407321 https://www.researchgate.net/publication/334407321_Modeling_Mammalian_Commitment_to_the_Neural_Lineage_Using_Embryos_and_Embryonic_Stem_Cells Modeling Mammalian Commitment to the Neural Lineage Using Embryos and Embryonic Stem Cells. July 2019. Frontiers in Physiology 10 DOI:10.3389/fphys.2019.00705
Author Rachel A. Shparberg, Hannah J. Glover, Michael B. Morris
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Copyright © 2019 Shparberg, Glover and Morris. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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current21:18, 29 April 2024Thumbnail for version as of 21:18, 29 April 20241,305 × 1,505 (636 KB)Rasbak (talk | contribs){{Information |description=Figure 4. Formation and patterning of the mouse neural tube. (A) The pseudostratified columnar epithelium of neural plate forms by 7.5 dpc. The lateral edges of the neural plate then (B) elevate and (C) fold by ~8.0 dpc before (D) converging at the midline and closing by ~8.5 dpc. Shh (red arrows) and BMP inhibitors secreted from the floor plate, and BMP4/7 (green arrows) secreted from the roof plate act to pattern the neural tube along its ventro-dorsal axis, givin...

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