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File:Glutamate-gated chloride channel receptor with bound ivermectin 3RHW.png

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Top-down and side views of the C. elegans glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel, bound to ivermectin. Ivermectin (royal blue) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits (pale blue), "locking" the receptor in an activated (open) conformation that allows unrestricted passage of chloride (Cl−) ions into the cell.

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Source Own work, after PDB 3RHW.
Author Fvasconcellos (talk · contribs)
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current17:49, 29 November 2020Thumbnail for version as of 17:49, 29 November 20201,200 × 2,470 (2.32 MB)Fvasconcellos (talk | contribs){{Information |Description=Top-down and side views of the ''C. elegans'' glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel, bound to {{w|ivermectin}}. Ivermectin (royal blue) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits (pale blue), "locking" the receptor in an activated (open) conformation that allows unrestricted passage of chloride (Cl<sup>−</sup>) ions into the cell. C...

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