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File:Hiv ligand receptor binding.jpg

Hiv_ligand_receptor_binding.jpg ‎(300 × 446 pixels, file size: 73 KB, MIME type: image/jpeg)

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Description Ligand-receptor binding. HIV-1 gp120 glycoprotein ligand (red); CD4-glycoprotein receptor (yellow); b12 antibody-protein ligand (green)
Date
Source National Institute of Allergy and Infectious Diseases, National Institute of Health
Author Peter Kwong, http://www3.niaid.nih.gov/labs/aboutlabs/VRC/structuralBiologyLaboratory/kwong.htm
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(Reusing this file)		 Public domain, NIH
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Summary edit

The gp120 envelope glycoprotein binds sequentially to the cellular receptors CD4 and a member of the chemokine receptor family (CXCR4 or CCR5) to initiate virus cell entry; Kwong et al., Nature, 420, 678-682 (12 December 2002). The antibody-protein binding to the CD4 receptor attempts to block the chemokine-receptor binding, thus prevent HIV-1 virus cell entry. Both gp120 and CD4 are glycoproteins Kwong et al., Nature 393, 648-659 (18 June 1998)

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current21:53, 6 December 2007Thumbnail for version as of 21:53, 6 December 2007300 × 446 (73 KB)Vql~commonswiki (talk | contribs){{Information |Description=Ligand-receptor binding. HIV-1 gp120 glycoprotein ligand (red); CD4-glycoprotein receptor (yellow); b12 antibody-protein ligand (green) |Source=National Institute of Allergy and Infectious Diseases, National Institute of Health

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