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File:Ipilimumab 5TRU.png

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Description Space-filling model of the Fab fragment of the monoclonal antibody ipilimumab (blue) bound to its target, CTLA-4 (pale green).
Style made to resemble the Protein Data Bank's "Molecule of the Month" series, illustrated by Dr. David S. Goodsell of the Scripps Research Institute. Created using QuteMol (http://qutemol.sourceforge.net). Optimized with OptiPNG.
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From PDB entry 5TRU. More information:

  • Ramagopal UA, Liu W, Garrett-thomson SC, et al. Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab. Proc Natl Acad Sci USA 2017;114(21):E4223-E4232. doi:10.1073/pnas.1617941114
Author Fvasconcellos (talk · contribs)
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current13:49, 28 July 2017Thumbnail for version as of 13:49, 28 July 20172,048 × 1,767 (152 KB)Fvasconcellos (talk | contribs)=={{int:filedesc}}== {{Information |Description={{w|Space-filling model}} of the {{w|Fragment antigen-binding|Fab fragment}} of the {{w|monoclonal antibody}} {{w|ipilimumab}} (blue) bound to its target, {{w|CTLA-4}} (pale green).<br>Style made to resem...

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