File:Mechanical-Strain-Stabilizes-Reconstituted-Collagen-Fibrils-against-Enzymatic-Degradation-by-pone.0012337.s002.ogv
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Mechanical-Strain-Stabilizes-Reconstituted-Collagen-Fibrils-against-Enzymatic-Degradation-by-pone.0012337.s002.ogv (Ogg Theora video file, length 5.0 s, 697 × 521 pixels, 1.69 Mbps, file size: 1.01 MB)
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editDescriptionMechanical-Strain-Stabilizes-Reconstituted-Collagen-Fibrils-against-Enzymatic-Degradation-by-pone.0012337.s002.ogv |
English: Degradation series contrasting strained and unstrained ROIs. Top Left) Entire field of view showing a collagen network, reconstituted around functionalized micropipettes, degrading in the presence of MMP-8. Bar = 10 µm. Top Right) ROI #4 - unstrained fibrils, including two perpendicular fibrils. Bar = 1 µm. Bottom Left) ROI #8 - strained fibrils. Note some fibrils within the strained ROI are perpendicular to the strain direction (Black Arrow), and these fibrils disappear before the strained fibrils. Bar = 1 µm. Bottom Right) Normalized, integrated edge intensity from ROI #4 (unstrained) and ROI#8 (strained) versus time. |
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Source | Video S1 from Flynn B, Bhole A, Saeidi N, Liles M, DiMarzio C, Ruberti J (2010). "Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)". PLOS ONE. DOI:10.1371/journal.pone.0012337. PMID 20808784. PMC: 2925882. | ||
Author | Flynn B, Bhole A, Saeidi N, Liles M, DiMarzio C, Ruberti J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 22:07, 30 October 2012 | 5.0 s, 697 × 521 (1.01 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Flynn B, Bhole A, Saeidi N, Liles M, DiMarzio C, Ruberti J |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Degradation series contrasting strained and unstrained ROIs. Top Left) Entire field of view showing a collagen network, reconstituted around functionalized micropipettes, degrading in the presence of MMP-8. Bar ? |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010 |