English: Rotation of the α-actinin rod domain dimer with molecular dynamics. One of the monomers in the α-actinin rod domain dimer was rotated using molecular dynamics. Rotation at both termini showed that the direction of rotation affects the torque required to achieve rotation (Figure 6B). Differences in torque required to achieve rotation arise from steric interactions between the monomers resisting rotation of one of the monomers. Shown here is rotation at terminus B in the clockwise direction. Rotation of one monomer (pink) involves both breaking of aromatic interactions (orange) and steric interaction with the other monomer (green). Rotation beyond 150 degrees introduces the steric interactions seen here and correlates to a peak in torque required to achieve rotation (Figure 6B).