This painting is the most important of this artist preserved in France. His subject is quite unusual: we see St. Anne, mother of the Virgin Mary, surrounded by her three successive husbands (Joachim, Cleophas and Salome). Among this enlarged Holy Family, one easily identifies, in the center, the Divine Child perched on his cradle, his mother who sustains him, and behind her, St. Anne with a white veil. On the left, appears St Jacques child leaning on his staff of pilgrim and, behind, Saint Antoine recognizable by his little bell. He is, with St. Francis of Assisi, visible on the far right, the only protagonist of the scene not to belong to the lineage of St. Anne.