English: Wt yeasts are mostly cleared by macrophages and surviving cells escape the phagocytes later than the Evo strain. Macrophages were infected with sonicated wild type yeast cells at a MOI of 2∶1. After 60 min of phagocytosis, non-attached yeasts were washed away and time-lapse microscopy was started. The majority of yeasts were cleared by macrophages within 48 hours (green arrows; 1, clearance after 7 h; 2, clearance after 40 h). Only some yeasts survived and replicated intracellularly (red arrow). After approximately 4 d, the number of extracellular yeasts increased and macrophages finally burst (examples shown with black arrows in temporal order).