File:Pleiotropic-Effects-of-Sox2-during-the-Development-of-the-Zebrafish-Epithalamus-pone.0087546.s012.ogv

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English: Downregulation of Notch results in more isl1+/sox2− cells in relation to controls at 15 ss. sox2 (red) is expressed in undifferentiated GFP-positive (green) pineal cells of Tg(flh:GFP) embryos, but it is downregulated in post-mitotic isl1-expressing cells (blue), in DMSO-treated embryos (left panel). DAPT treatment (right panel) leads to increased number of isl-positive cells and thus broader sox2-negative domain. Navigation through the optical stacks starting with the dorsal-most optical section of the pineal anlage and moving ventrally.
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Source Movie S1 from Pavlou S, Astell K, Kasioulis I, Gakovic M, Baldock R, van Heyningen V, Coutinho P (2014). "Pleiotropic Effects of Sox2 during the Development of the Zebrafish Epithalamus". PLOS ONE. DOI:10.1371/journal.pone.0087546. PMC: 3909122.
Author Pavlou S, Astell K, Kasioulis I, Gakovic M, Baldock R, van Heyningen V, Coutinho P
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Date/TimeThumbnailDimensionsUserComment
current21:56, 5 February 20142.7 s, 1,399 × 696 (181 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 720P 226 kbps Completed 22:00, 13 October 2018 3.0 s
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WebM 360P 443 kbps Completed 21:56, 5 February 2014 3.0 s
Streaming 144p (MJPEG) 315 kbps Completed 04:18, 19 November 2023 2.0 s

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