File:Pleiotropic-Effects-of-Sox2-during-the-Development-of-the-Zebrafish-Epithalamus-pone.0087546.s012.ogv
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DescriptionPleiotropic-Effects-of-Sox2-during-the-Development-of-the-Zebrafish-Epithalamus-pone.0087546.s012.ogv |
English: Downregulation of Notch results in more isl1+/sox2− cells in relation to controls at 15 ss. sox2 (red) is expressed in undifferentiated GFP-positive (green) pineal cells of Tg(flh:GFP) embryos, but it is downregulated in post-mitotic isl1-expressing cells (blue), in DMSO-treated embryos (left panel). DAPT treatment (right panel) leads to increased number of isl-positive cells and thus broader sox2-negative domain. Navigation through the optical stacks starting with the dorsal-most optical section of the pineal anlage and moving ventrally. |
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Source | Movie S1 from Pavlou S, Astell K, Kasioulis I, Gakovic M, Baldock R, van Heyningen V, Coutinho P (2014). "Pleiotropic Effects of Sox2 during the Development of the Zebrafish Epithalamus". PLOS ONE. DOI:10.1371/journal.pone.0087546. PMC: 3909122. | ||
Author | Pavlou S, Astell K, Kasioulis I, Gakovic M, Baldock R, van Heyningen V, Coutinho P | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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current | 21:56, 5 February 2014 | 2.7 s, 1,399 × 696 (181 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Pavlou S, Astell K, Kasioulis I, Gakovic M, Baldock R, van Heyningen V, Coutinho P |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Downregulation of Notch results in more isl1+/sox2? cells in relation to controls at 15 ss. sox2 (red) is expressed in undifferentiated GFP-positive (green) pineal cells of Tg(flh:GFP) embryos, but it is downregulated in post-mitotic isl1-expressing cells (blue), in DMSO-treated embryos (left panel). DAPT treatment (right panel) leads to increased number of isl-positive cells and thus broader sox2-negative domain. Navigation through the optical stacks starting with the dorsal-most optical section of the pineal anlage and moving ventrally. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014 |