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File:Rapid-and-Direct-Transport-of-Cell-Surface-APP-to-the-Lysosome-defines-a-novel-selective-pathway-1756-6606-3-11-S1.ogv

Rapid-and-Direct-Transport-of-Cell-Surface-APP-to-the-Lysosome-defines-a-novel-selective-pathway-1756-6606-3-11-S1.ogv ‎(Ogg Theora video file, length 20 s, 562 × 594 pixels, 495 kbps, file size: 1.18 MB)

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English: Image stack demonstrating APP preferentially localized in the lysosome a neuronal SN56 cell. SN56 cells were transiently co-transfected with βAPP-CFP (green) and LAMP1-mRFP (red). Image stack was acquired on a Zeiss LSM510 confocal microscope. The first segment shows βAPP-CFP in green. The second segment of the video shows LAMP1-mrfp overlaid in red. In the third segment, a colocalization channel, showing the colocalization of the brightest 2% of red and green pixels is overlaid in white. QuickTime video was generated using Imaris 6.1.5 software to perform volume rendering and animation.
Date
Source Lorenzen A, Samosh J, Vandewark K, Anborgh P, Seah C, Magalhaes A, Cregan S, Ferguson S, Pasternak S (2010). "Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway". Molecular Brain. DOI:10.1186/1756-6606-3-11. PMID 20409323. PMC: 2868040.
Author Lorenzen A, Samosh J, Vandewark K, Anborgh P, Seah C, Magalhaes A, Cregan S, Ferguson S, Pasternak S
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This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
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Date/TimeThumbnailDimensionsUserComment
current00:08, 20 November 201220 s, 562 × 594 (1.18 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 159 kbps Completed 00:11, 17 October 2018 11 s
Streaming 480p (VP9) Not ready Unknown status
VP9 360P 98 kbps Completed 00:11, 17 October 2018 9.0 s
Streaming 360p (VP9) Not ready Unknown status
VP9 240P 60 kbps Completed 00:11, 17 October 2018 6.0 s
Streaming 240p (VP9) 61 kbps Completed 14:25, 16 December 2023 0.0 s
WebM 360P 511 kbps Completed 04:43, 20 November 2012 9.0 s
Streaming 144p (MJPEG) 277 kbps Completed 10:40, 18 November 2023 1.0 s

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