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File:Skin-Cornification-Proteins-Provide-Global-Link-between-ROS-Detoxification-and-Cell-Migration-pone.0011957.s003.ogv

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English: Involvement of SPRR proteins in cell migration. OKF keratinocytes were transiently transfected with pEGFP-SPRR1B and analyzed with the Olympus IX81 live-imaging station. Time-lapse images were recorded for 200 min at intervals of 2 min. Note the localization of SPRR proteins to membrane ruffles at the leading edge of migrating cells. This pattern was not observed in parallel cultures expressing pEGFP-actin or pEGFP-tubulin fusion proteins and was confirmed by SPRR-antibody staining. SPRR proteins were also consistently found in the nuclei of these cells.
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Source Movie S1 from Vermeij W, Backendorf C (2010). "Skin Cornification Proteins Provide Global Link between ROS Detoxification and Cell Migration during Wound Healing". PLOS ONE. DOI:10.1371/journal.pone.0011957. PMID 20689819. PMC: 2914756.
Author Vermeij W, Backendorf C
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current04:09, 17 November 20129.9 s, 840 × 704 (2.88 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 480P 306 kbps Completed 13:51, 10 January 2023 8.0 s
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