File:T.suis Immuno-modulatory mechanisms.png
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English: Cascade of immuno-molecular events hypothesized to lead to the modulation of immune response in Trichuris suis-infected humans. Molecules linked to the T-cell receptor and chemokine signalling pathways could be involved in the stimulation of the Th2-type immune response, which, in turn, stimulates the expansion of populations of pro-inflammatory cells and cytokines. T. suis homologues of secreted leukocyte protease inhibitors (SLPIs) could inhibit hyper-responsiveness of the immune system by down-regulating the activity of Th2-type cells. |
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http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023590
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Author | Cinzia Cantacessi, Neil D. Young, Peter Nejsum, Aaron R. Jex, Bronwyn E. Campbell, Ross S. Hall, Stig M. Thamsborg, Jean-Pierre Scheerlinck, Robin B. Gasser | ||
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