File:The fluorescence lifetime imaging microscopy (FLIM) of the cystic fibrosis transmembrane conductance regulator (CFTR) constructs tagged with enhanced cyan fluorescent protein (ECFP).jpg
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editDescriptionThe fluorescence lifetime imaging microscopy (FLIM) of the cystic fibrosis transmembrane conductance regulator (CFTR) constructs tagged with enhanced cyan fluorescent protein (ECFP).jpg |
English: The fluorescence lifetime map of the most common disease causing variant of cystic fibrosis transmembrane conductance regulator (CFTR) tagged with enhanced cyan fluorescent protein (ECFP), F508-CFTR-ECFP (the middle image) flanked by the images of the wild type CFTR constructs tagged with ECFP. The F508-CFTR is a processing mutation that interferes with folding and trafficking of CFTR. This mutated version of CFTR prevents a close association between F508-CFTR and Epithelial Na+ Channel (ENaC) unless F508-CFTR is rescued by chemical correctors and low temperature (the second and the sixth images from the left). Also shown are the fluorescence lifetime images of negative and the positive FLIM constructs (the first image and the last images, respectively). |
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Author | Bakhrom K. Berdiev |
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This image was uploaded as part of European Science Photo Competition 2015. |
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current | 12:00, 8 January 2016 | ![]() | 816 × 1,056 (41 KB) | Bakhrom.berdiev (talk | contribs) | User created page with UploadWizard |
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