File:4-aminobutanoate (GABA) degradation pathway.png

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Butanoyl-CoA participates as an intermediate in the pathway

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English: 4-aminobutanoate (GABA) has two fates in the cell. When discovered in Acetoanaerobium sticklandii and Pseudomonas fluorescens, 4-aminobutanoate was converted into L-glutamate, which was transaminated, releasing ammonium. However, in Acetoanaerobium sticklandii and Clostridium aminobutyricum, 4-aminobutanoate was converted into succinate semialdehyde and, through a series of steps via the intermediate of butanoyl-CoA, finally converted into butanoate.
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Source https://metacyc.org/pathway?orgid=META&id=PWY-5022&detail-level=1#
Author Ron Caspi, SRI International

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