File:Amino acid metabolism in triple-negative breast cancer cells.jpg

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Amino acid metabolism in triple-negative breast cancer cells.

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English: Amino acid metabolism in triple-negative breast cancer cells. The glutamine, serine and glycine metabolic pathways are significantly upregulated. The upregulated expression of key genes within the glutamine, serine and glycine metabolic pathways have also been observed in triple-negative breast cancer cells. 3PG, 3-phospho-glycerate; pPYR, phosphohydroxypyruvate; GSH, reduced glutathione; OAA, oxaloacetate; α-KG, α-ketoglutarate; GLU, glutamate; GLUT1, glucose transporter1; PHGDH, phosphoglycerate dehydrogenase; PSAT1, phosphoserine aminotransferase 1; PSPH, phosphoserine phosphatase; SHMT, serine hydroxymethyltransferase; SLC1A5, solute carrier family 1 member 5; xCT, cystine/glutamate antiporter; GLS, glutaminase; GLUD, glutamate dehydrogenase; ASNS, asparagine synthetase.
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Source https://www.frontiersin.org/articles/10.3389/fonc.2020.00428/full#B40
Author Xiangyu Sun, Mozhi Wang, Mengshen Wang, Xueting Yu, Jingyi Guo, Tie Sun, Xinyan Li, Litong Yao, Haoran Dong and Yingying Xu

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current07:12, 18 March 2022Thumbnail for version as of 07:12, 18 March 20221,084 × 740 (270 KB)Andrawaag (talk | contribs)Uploaded a work by Xiangyu Sun, Mozhi Wang, Mengshen Wang, Xueting Yu, Jingyi Guo, Tie Sun, Xinyan Li, Litong Yao, Haoran Dong and Yingying Xu from https://www.frontiersin.org/articles/10.3389/fonc.2020.00428/full#B40 with UploadWizard

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