File:Amlodipine and major metabolite.svg
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DescriptionAmlodipine and major metabolite.svg |
English: Amlodipine and one of its major metabolites. The amine group is oxidated and the side ester chains are hydrolyzed.
Español: Amlodipino y uno de sus metabolitos principales. El se oxida el grupo amino y se hidrolizan los grupos de éster. |
Date | |
Source | Own work |
Author | Persia Salehi |
References:
- Zhu, Yanlin; Wang, Fen; Li, Quan; Zhu, Mingshe; Du, Alicia; Tang, Wei; Chen, Weighing (2014). "Amlodipine Metabolism in Human Liver Microsomes and Roles of CYP3A4/5 in the Dihydropyridine Dehydrogenation". Drug Metabolism and Disposition 42 (2): 245-249. DOI:10.1124/dmd.113.055400. PMID 24301608. ISSN 0090-9556.
Made using the chemfig
package in LaTex.
\documentclass[10pt]{article} \usepackage{chemfig} \setdoublesep{0.091 cm} % Bond Spacing \setatomsep{14.4 pt} % Bond length \setcrambond{2 pt}{1 pt}{2.5 pt} % {Bold width}{1pt}{Hash spacing} \setbondoffset{1.6 pt} % Margin Width \setbondstyle{line width=0.6 pt} % Line width \renewcommand*\printatom[1]{\normalsize \ensuremath{\mathsf{#1}}} \begin{document} \schemestart \chemfig{ -[:90]O -[:30] (=[:90,0.75]O) -[:-30] *6( = (-[:210]) -\chembelow{N}{H} - (-[:-30] -[:30]O -[:-30] -[:30] -[:-30]NH_2 ) = ( -[:30](=[:90,0.75]O) -[:-30]O -[:30] ) - ( -[:90,1.5] *6( - (-[,.75]Cl) = - = - = ) ) - ) } \arrow{->} \hspace{0.7 cm} \chemfig{ -[:90]O -[:30] (=[:90,0.75]O) -[:-30] *6( =[,,,,magenta] (-[:210]) -[,,,,magenta]\color{magenta}{N} =[,,,,magenta] (-[:-30] -[:30]\color{magenta}{OH} ) -[,,,,magenta] ( -[:30](=[:90,0.75]O) -[:-30]\color{magenta}{OH} ) =[,,,,magenta] ( -[:90,1.5] *6( - (-[,.75]Cl) = - = - = ) ) -[,,,,magenta] ) } \schemestop \end{document}
Licensing edit
Public domainPublic domainfalsefalse |
This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship. |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 04:32, 12 July 2017 | 302 × 106 (15 KB) | Prof. Squirrel (talk | contribs) | Changed to comply with Wikipedia style guide for chemicals | |
17:01, 4 July 2017 | 362 × 130 (17 KB) | Prof. Squirrel (talk | contribs) | User created page with UploadWizard |
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Width | 302.333px |
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Height | 105.667px |