File:Analysis-of-Meiosis-in-SUN1-Deficient-Mice-Reveals-a-Distinct-Role-of-SUN2-in-Mammalian-Meiotic-pgen.1004099.s002.ogv
Analysis-of-Meiosis-in-SUN1-Deficient-Mice-Reveals-a-Distinct-Role-of-SUN2-in-Mammalian-Meiotic-pgen.1004099.s002.ogv (Ogg Theora video file, length 5.1 s, 550 × 500 pixels, 856 kbps, file size: 537 KB)
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DescriptionAnalysis-of-Meiosis-in-SUN1-Deficient-Mice-Reveals-a-Distinct-Role-of-SUN2-in-Mammalian-Meiotic-pgen.1004099.s002.ogv |
English: 3-dimensional reconstructions of entire spermatocyte nuclei showing clustered and non-clustered telomere patterns. Representative spermatocytes of paraffin testis sections of Sun1(Δex10-11) wildtype and knockout males labeled by KASH5 (green) and SYCP3 (red). Non-clustered KASH5 foci, marking telomeres attached to the NE, in pachytene cells and clustered KASH5 foci representing the earlier bouquet stage can clearly be observed in wildtype spermatocytes. In SUN1 deficient spermatocytes, non-clustered and clustered patterns of KASH5 foci can also be observed. Here, clustered KASH5 foci also represent bouquet-like formations of successfully attached telomeres. Scale bars 5 µm. |
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Source | Video S1 from Link J, Leubner M, Schmitt J, Göb E, Benavente R, Jeang K, Xu R, Alsheimer M (2014). "Analysis of Meiosis in SUN1 Deficient Mice Reveals a Distinct Role of SUN2 in Mammalian Meiotic LINC Complex Formation and Function". PLOS Genetics. DOI:10.1371/journal.pgen.1004099. PMID 24586178. PMC: 3937131. | |||
Author | Link J, Leubner M, Schmitt J, Göb E, Benavente R, Jeang K, Xu R, Alsheimer M | |||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 01:29, 11 December 2014 | 5.1 s, 550 × 500 (537 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Link J, Leubner M, Schmitt J, Göb E, Benavente R, Jeang K, Xu R, Alsheimer M |
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Usage terms | http://creativecommons.org/publicdomain/zero/1.0/ |
Image title | 3-dimensional reconstructions of entire spermatocyte nuclei showing clustered and non-clustered telomere patterns. Representative spermatocytes of paraffin testis sections of Sun1(Δex10-11) wildtype and knockout males labeled by KASH5 (green) and SYCP3 (red). Non-clustered KASH5 foci, marking telomeres attached to the NE, in pachytene cells and clustered KASH5 foci representing the earlier bouquet stage can clearly be observed in wildtype spermatocytes. In SUN1 deficient spermatocytes, non-clustered and clustered patterns of KASH5 foci can also be observed. Here, clustered KASH5 foci also represent bouquet-like formations of successfully attached telomeres. Scale bars 5 µm. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014-02 |