File:Annalisa Pastore speaks at Scuola Normale Superiore.jpg
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DescriptionAnnalisa Pastore speaks at Scuola Normale Superiore.jpg |
English: http://www.sns.it/eventi/iron-sulfur-...
Colloqui della Classe di Scienze Annalisa Pastore, King’s College, London e Università di Pavia Iron sulfur cluster: from the crucible of life to a rare disease Abstract: Iron sulfur clusters, non amino acidic groups attached to proteins to assist them in their functions, are required to sustain fundamental cellular pathways. Being ubiquitous and evolutionarily ancient, they are thought to be the first response to the problem of storing iron and sulfur, two essential but toxic elements, in a bioavailable form. Iron sulfur clusters are at the very centre of life and have also been suggested to be present in the Last Universal Common Ancestor (LUCA). Cluster formation requires complex machines constituted by an intricate network of proteins and electron transfer pathways which we are only recently starting to understand. Modifications of any of the components of these machines result in disease. In my seminar I shall review our current knowledge and discuss our contributions to the field. |
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Date | |||
Source | Annalisa Pastore, Iron sulfur cluster: from the crucible of life to a rare disease - 26 aprile 2017, at 4:36, cropped | ||
Author | Scuola Normale Superiore | ||
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Annalisa Pastore, Iron sulfur cluster: from the crucible of life to a rare disease - 26 aprile 2017, at 4:36, cropped, was reviewed on 11 November 2019 by reviewer Leoboudv, who confirmed that it was available there under the stated license on that date.
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