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File:Celula beta estructura granulos.png

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Español: Figura 7. Cambios ultraestructurales en células β RIP-Cre Dicer1 Δ/Δ .

A. Micrografía electrónica de células β de ratones control de 11 semanas de edad ( arriba ) y RIP-Cre Dicer1 Δ/Δ ( abajo ).
En las imágenes de la izquierda (bajo aumento), la membrana plasmática que rodea a la célula β analizada está marcada con una línea negra. El área dentro del rectángulo punteado se muestra en las imágenes de mayor aumento a la derecha.
Los gránulos acoplados están marcados con flechas negras en las imágenes de la derecha.
Barras de escala de 2 µm (imágenes de la izquierda) y 0,5 µm (imágenes de la derecha).

β: célula β; α: célula α; δ: célula δ; N: núcleo; g: gránulo; m: mitocondrias.
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Source Beta-Cell Specific Deletion of Dicer1 Leads to Defective Insulin Secretion and Diabetes Mellitus. (2011) PLoS ONE 6(12): e29166. doi:10.1371/journal.pone.0029166
Author Martins Kalis, Caroline Bolmeson, Jonathan L. S. Esguerra, Shashank Gupta, Anna Edlund, Neivis Tormo-Badia, Dina Speidel, Dan Holmberg, Sofia Mayans, Nelson K. S. Khoo, Anna Wendt, Lena Eliasson, Corrado M. Cilio

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