File:Colonic epithelia from mice with colonic tumorigenesis (A, B), or mice without colonic tumorigenesis (C, D), immunostained (brown) for 8-oxo-dG, cell nuclei stained daark blue with hematoxylin. Scale bars show 50 microns.jpg
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edit,_or_mice_without_colonic_tumorigenesis_(C,_D),_immunostained_(brown)_for_8-oxo-dG,_cell_nuclei_stained_daark_blue_with_hematoxylin._Scale_bars_show_50_microns.jpg&action=edit§ion=1){kind=link}
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English: The level of 8-oxo-dG was graded in the nuclei of colonic crypt cells on a scale of 0-4. Mice progressing to tumors had 8-oxo-dG in colonic crypts at levels 3 to 4 (A, B) while mice without tumorigenesis had crypt 8-oxo-dG at levels 0 to 2 (C, D). Tumorigenesis was induced by adding deoxycholate to the mouse diet to give a level of deoxycholate in the mouse colon similar to the level in the colon of humans on a high fat diet.[1]
The images were made from original photomicrographs, but were also included in an article[1] and illustrations were published with Creative Commons Attribution-Noncommercial License allowing re-use. |
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| Author | Chaya5260 |
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| current | 00:52, 14 July 2015 | | 1,980 × 1,592 (709 KB) | Chaya5260 (talk | contribs) | User created page with UploadWizard |
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