File:Contribution of EMT to cancer progression.jpg
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editDescriptionContribution of EMT to cancer progression.jpg |
Figure 5. Contribution of EMT to cancer progression |
Date | |
Source | https://www.jci.org/articles/view/39104 The basics of epithelial-mesenchymal transition J Clin Invest. 2009;119(6):1420-1428. https://doi.org/10.1172/JCI39104. |
Author | Raghu Kalluri, Robert A. Weinberg |
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current | 00:35, 20 May 2024 | 1,704 × 344 (425 KB) | Rasbak (talk | contribs) | {{Information |description=Figure 5. Contribution of EMT to cancer progression<br> Progression from normal epithelium to invasive carcinoma goes through several stages. The invasive carcinoma stage involves epithelial cells losing their polarity and detaching from the basement membrane. The composition of the basement membrane also changes, altering cell-ECM interactions and signaling networks. The next step involves EMT and an angiogenic switch, facilitating the malignant phase of tumor grow... |
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