File:DFMO inhibitor product evidence.svg
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editDescriptionDFMO inhibitor product evidence.svg |
English: Experimental evidence for the proposed end structure (top) formed upon ODC inhibition by DFMO (Eflornithine). The reduced (left) and oxidized (right) derivatives of the proposed end structure were detected by mass spectrometry. Reference: Poulin R, Lu L, Ackermann B, Bey P, Pegg AE (1992). "Mechanism of the irreversible inactivation of mouse ornithine decarboxylase by alpha-difluoromethylornithine. Characterization of sequences at the inhibitor and coenzyme binding sites". The Journal of Biological Chemistry 267 (1): 150–8. PMID 1730582. |
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Author | Hbf878 |
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