File:Dose-dependent reshaping of primitive streak.jpg
Size of this preview: 469 × 599 pixels. Other resolutions: 188 × 240 pixels | 376 × 480 pixels | 968 × 1,236 pixels.
Original file (968 × 1,236 pixels, file size: 743 KB, MIME type: image/jpeg)
Captions
Captions
Add a one-line explanation of what this file represents
Summary
edit
| Description | Fig. 2. Dose-dependent reshaping of primitive streak. (A-F,S,T) Dorsal views of control (A, Sa and top row of T) and ROCK-inhibited embryos (B-F, Sb-Se and bottom row of T) analysed for brachyury (A-F, Sa-Se), wnt3, nodal, dickkopf1, cerberus and chordin (all in T) in sagittal (G-K) or transversal (L-R) sections. Anterior is to the top in dorsal views and to the left in sagittal sections. Black dots mark posterior embryonic disc borders. Asterisks mark epiblast-trophoblast border. Arrows mark the position of the epithelio-mesenchymal hinge (EMH) in H and L and the chordoneural hinge in J. (M) High magnification of occasional mesoderm cells (red) in the brachyury-negative area shown in L. (N) Transversal semithin section from presumptive primitive streak area showing one half of a treated embryo (midline is near the right edge). Box indicates the area shown in O. (O) Ultrathin section showing bottle cell (blue), mesodermal cell (pink) and hypoblast cell (yellow). (P,Q) Epiblast cells from the PGE area (P) and from the anterior half of the embryonic disc (Q). (R) Trophoblast cell. Arrowheads point to the existing basement membrane (Q,R). (S) Drawing of mesoderm displacement by ROCK inhibition: Mammotypic (a), reptilian-like (b), amniote precursor-like (c,d) and amphibian-like or teleost-like (e) gastrulation centres. Dark blue colour marks EMT area. Red dotted lines indicate the border of the EMH. Light blue colour marks the EMT-free epiblast. Curved arrows indicate the dorso-ventral direction of EMT and subsequent lateral mesoderm migration. e, epiblast; h, hypoblast; m, mesoderm; n, node. Scale bar in A: 100 µm for A-F, T; 50 µm for G, I, L; 25 µm for H, J, K, M; scale bar in P: 10 µm for N, 2 µm for O, 1 µm for P-R. |
| Date | |
| Source | https://journals.biologists.com/dev/article/142/1/92/46970/Rho-kinase-activity-controls-directional-cell Rho kinase activity controls directional cell movements during primitive streak formation in the rabbit embryo. Development. 2015 Jan 1;142(1):92-8. doi: 10.1242/dev.111583. PMID: 25516971; PMCID: PMC4299133. |
| Author | Stankova V, Tsikolia N, Viebahn C. |
|
This file, which was originally posted to an external website, has not yet been reviewed by an administrator or reviewer to confirm that the above license is valid. See Category:License review needed for further instructions.
|
© 2015. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
Licensing
edit
This file is licensed under the Creative Commons Attribution 3.0 Unported license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 21:17, 28 April 2024 | | 968 × 1,236 (743 KB) | Rasbak (talk | contribs) | {{Information |description=Fig. 2. Dose-dependent reshaping of primitive streak. (A-F,S,T) Dorsal views of control (A, Sa and top row of T) and ROCK-inhibited embryos (B-F, Sb-Se and bottom row of T) analysed for brachyury (A-F, Sa-Se), wnt3, nodal, dickkopf1, cerberus and chordin (all in T) in sagittal (G-K) or transversal (L-R) sections. Anterior is to the top in dorsal views and to the left in sagittal sections. Black dots mark posterior embryonic disc borders. Asterisks mark epiblast-trop... |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
