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Foxp3

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Description
English: FIGURE 3. Foxp3 alterations in inflammation, autoimmunity, and IPEX. Inflammation, autoimmune diseases and IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome are associated with alteration of Foxp3 gene expression, stability, and function. Lipopolysaccharides (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-18, STIP1 homology and U-Box containing protein (Stub)1, Forkhead box-p3 (Foxp3), signal transducer activator of transcription (STAT)3, Id2, and interferon (IFN)-γ, Deleted in breast cancer 1 (DBC1) factor, enhancer of zeste (Ezh)2, DNA-methyltransferase 3a (Dnmt3a), Foxp3-Exon2 (Foxp3-E2), interleukin-2 receptor alpha chain (IL-2RA), tat-interactive protein 60 kDa (TIP60), and RAR-related orphan receptor (ROR)γt.
Date
Source https://www.frontiersin.org/articles/10.3389/fimmu.2019.03136/full
Author Colamatteo A, Carbone F, Bruzzaniti S, Galgani M, Fusco C, Maniscalco GT, Di Rella F, de Candia P, De Rosa V.

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