Up to 4 years of age was like other children, according to his mother's account, and the eyes and head were natural. Then the sight began to fail and the head gradually altered its shape and the eyes became prominent. Never fits -suffered from frequent headache. Past and family history good. Very intelli. gent, learned blind reading at an early age. Typical oxycephaly with ex- ophthalmos, divergent squint, and marked nystagmus. Could barely distinguish large objects. Slight deflexion of nasal septum. Hard palate arched but not nearly so deformed as in Case I. Hearing, taste, and smell normal. There were no other malformations. The skiagram shows the same features as in Case I, the distinct digital markings and the changes in the orbits and