File:Glucose metabolism in triple-negative breast cancer cells.jpg

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Glucose metabolism in triple-negative breast cancer cells.

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English: The glycolytic pathway is significantly upregulated in triple-negative breast tumors. The genes coding the key glycolytic enzymes are overexpressed in triple-negative breast tumors. TCA, tricarboxylic acid cycle; G6P, glucose-6-phosphate; F6P, fructose-6-phosphate; F1,6P, fructose-1,6-bisphosphate; PEP, phosphoenolpyruvate; OAA, oxaloacetate; α-KG, α-ketoglutarate; GLUT, glucose transporter; HK, hexokinase; PFK, phosphofructokinase; PKM2, pyruvate kinase isozyme type 2; LDHA, lactate dehydrogenase A; MCT1, monocarboxylate transporter 1; PDK1, pyruvate dehydrogenase kinase 1; PDH, pyruvate dehydrogenase.
Date
Source https://www.frontiersin.org/articles/10.3389/fonc.2020.00428/full#:~:text=Amino%20acid%20metabolism%20in%20triple,triple%2Dnegative%20breast%20cancer%20cells.
Author Xiangyu Sun, Mozhi Wang, Mengshen Wang, Xueting Yu, Jingyi Guo, Tie Sun, Xinyan Li, Litong Yao, Haoran Dong and Yingying Xu

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