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English: Heterozygosity vs. Proportion of European Ancestry in Mestizo Populations. The heterozygosity predicted from the estimated ancestry of a population was calculated as described in Methods. A positive correlation (ρ = 0.758, P<0.01) is observed between autosomal heterozygosity and European ancestry (Figure 3). This increase in heterozygosity with higher European ancestry agrees well with expectations, based on the difference in mean diversity of European and Native American populations and their genetic differentiation, as measured by FST (ρ = 0.786, P<0.01; See Methods).
Date Published: March 21, 2008
Source Wang S, Ray N, Rojas W, Parra MV, Bedoya G, Gallo C, et al. (2008) Geographic Patterns of Genome Admixture in Latin American Mestizos. PLoS Genet 4(3): e1000037. doi:10.1371/journal.pgen.1000037 http://journals.plos.org/plosgenetics/article?id=10.1371%2Fjournal.pgen.1000037
Author Sijia Wang, Nicolas Ray, Winston Rojas, Maria V. Parra, Gabriel Bedoya, Carla Gallo, Giovanni Poletti, Guido Mazzotti, Kim Hill, Ana M. Hurtado, Beatriz Camrena, Humberto Nicolini, William Klitz, Ramiro Barrantes, Julio A. Molina, Nelson B. Freimer, Maria Cátira Bortolini, Francisco M. Salzano, Maria L. Petzl-Erler, Luiza T. Tsuneto, José E. Dipierri, Emma L. Alfaro, Graciela Bailliet, Nestor O. Bianchi, Elena Llop, Francisco Rothhammer, Laurent Excoffier, Andrés Ruiz-Linares
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Ancestry Proportions in 13 Mestizo Populations
Native American Ancestry Proportions (European and African components are not shown)
Native American Ancestry Proportions detailed (European and African components are not shown)
Approximate geographic location of the Mestizo and Native American populations
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