File:Imaging-the-Impact-of-Chemically-Inducible-Proteins-on-Cellular-Dynamics-In-Vivo-pone.0030177.s006.ogv
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Imaging-the-Impact-of-Chemically-Inducible-Proteins-on-Cellular-Dynamics-In-Vivo-pone.0030177.s006.ogv (Ogg Theora video file, length 6.0 s, 450 × 225 pixels, 989 kbps, file size: 724 KB)
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editDescriptionImaging-the-Impact-of-Chemically-Inducible-Proteins-on-Cellular-Dynamics-In-Vivo-pone.0030177.s006.ogv |
English: In vivo imaging of Shield-1 mediated induction of tunable E-cadherin in 231LN cells. 231LN micrometastatic colonies expressing tunable E-cadh-zsG-DD protein were treated with Shield-1 ligand to achieve a final in vivo concentration of 0.5 µM resulting in an induction effect within 24 hours of Shield-1 injection. During the induction phase, an epithelial morphology is maintained for 12 hours. Images were acquired every 15 minutes in the green (E-cadh-zsG-DD) and red (tdTomato) channels. Movie consists of maximum intensity projections for each timepoint and corresponds to Figure 7C. |
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Source | Movie S6 from Leong H, Lizardo M, Ablack A, McPherson V, Wandless T, Chambers A, Lewis J (2012). "Imaging the Impact of Chemically Inducible Proteins on Cellular Dynamics In Vivo". PLOS ONE. DOI:10.1371/journal.pone.0030177. PMID 22276156. PMC: 3261888. | ||
Author | Leong H, Lizardo M, Ablack A, McPherson V, Wandless T, Chambers A, Lewis J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 00:49, 30 October 2012 | 6.0 s, 450 × 225 (724 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Leong H, Lizardo M, Ablack A, McPherson V, Wandless T, Chambers A, Lewis J |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012 |