File:Imp-GFP localisation in the Drosophila oocyte.png
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English: Localisation of the mRNA binding protein Imp in ribonucleoprotein complexes in the Drosophila melanogaster egg chamber, being transported from the nurse cells to the oocyte. Evidence that microtubule motors are important. (A, A') GFP-Imp expression in wild type egg chambers is enriched in the oocyte and localizes to the posterior of the oocyte in stage 10.
(B, B') Disruption of dynein using ΔGl overexpression (or the Dhc 6–6/6–12 transheterozygous mutant background; data not shown) produces an early aberrant accumulation of GFP-Imp to the oocyte anterior. However, the subsequent accumulation to the posterior pole is not affected. (C, C') In germline clones homozygous for the kinesin null mutation, khc27, GFP-Imp enrichment in the early oocyte is retained, but later accumulation at the posterior of the oocyte is lost. Bar (applies to all images), 10 μm. |
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| Date | |||
| Source | Boylan KLM, Mische S, Li M, Marqués G, Morin X, et al. (2008) Motility Screen Identifies Drosophila IGF-II mRNA-Binding Protein—Zipcode-Binding Protein Acting in Oogenesis and Synaptogenesis. PLoS Genet 4(2): e36. doi:10.1371/journal.pgen.0040036 [1] | ||
| Author | Kristin L. M. Boylan, Sarah Mische, Mingang Li, Guillermo Marqués, Xavier Morin, William Chia, Thomas S. Hays | ||
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| Other versions | Derivative works of this file: Ribonucleoprotein particles in the Drosophila egg chamber.png |
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| current | 19:32, 3 July 2009 | | 1,671 × 1,871 (1.26 MB) | Celefin~commonswiki (talk | contribs) | {{Information |Description={{en|1=Localisation of the mRNA binding protein Imp in ribonucleoprotein complexes in the ''Drosophila melanogaster'' egg chamber, being transported from the nurse cells to the oocyte. Evidence that microtubule motors are import |
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