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File:Influence of pigmentation on skin cancer risk.png

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Fitzpatrick Scale
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Summary edit

Description
English: Influence of pigmentation on skin cancer risk. Fair-skinned individuals with low levels of melanin in the epidermis display a UV sensitive phenotype, tending to burn rather than tan, after UV exposure. Recent data suggest that mutations that contribute to fair complexion and tanning impairment, specifically signaling defects in the melanocortin 1 receptor (MC1R), may also be associated with less efficient DNA repair in melanocytes. MC1R-defective individuals not only suffer higher realized doses of UV radiation because their skin is less able to block UV photons, but they may also accumulate more mutations from UV exposure because of defective DNA repair.
Date Published: 7 June 2013
Source John D’Orazio et al. "UV Radiation and the Skin" Int. J. Mol. Sci. 2013, 14(6), 12222-12248; doi:10.3390/ijms140612222 http://www.mdpi.com/1422-0067/14/6/12222/htm
Author John D’Orazio, Stuart Jarrett, Alexandra Amaro-Ortiz and Timothy Scott

Licensing edit

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File history

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Date/TimeThumbnailDimensionsUserComment
current04:56, 18 April 2021Thumbnail for version as of 04:56, 18 April 20211,276 × 490 (260 KB)JPxG (talk | contribs)fix strange, extraterrestrial eyes
00:13, 18 January 2018Thumbnail for version as of 00:13, 18 January 20181,276 × 490 (273 KB)Erulas (talk | contribs)Reverted to version as of 00:07, 18 January 2018 (UTC)
00:13, 18 January 2018Thumbnail for version as of 00:13, 18 January 20182,754 × 1,054 (8.31 MB)Erulas (talk | contribs)Accidentally uploaded the original rather than the edited file
00:07, 18 January 2018Thumbnail for version as of 00:07, 18 January 20181,276 × 490 (273 KB)Erulas (talk | contribs)Removed lazy and inaccurate racial categories that accompanied the skin tone types. Asians and Native Americans were glossed over as homogeneous categories even though their skin tones span nearly the entire Fitzpatrick scale. Austronesians were crudel...
20:09, 23 June 2016Thumbnail for version as of 20:09, 23 June 20162,754 × 1,447 (555 KB)Was a bee (talk | contribs){{Information |Description={{en|1=Influence of pigmentation on skin cancer risk. Fair-skinned individuals with low levels of melanin in the epidermis display a UV sensitive phenotype, tending to burn rather than tan, after UV exposure. Recent data sugg...

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