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English: K02288, identified as an inhibitor of the bone morphogenetic protein (BMP) receptor kinase ALK2 (ACVR1), a candidate for treatment of the debilitating genetic disorder Fibrodysplasia ossificans progressiva.
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Source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639963/
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Caroline E. Sanvitale,1 Georgina Kerr,1 Apirat Chaikuad,1 Marie-Christine Ramel,2 Agustin H. Mohedas,3 Sabine Reichert,2 You Wang,4 James T. Triffitt,5 Gregory D. Cuny,4,¤ Paul B. Yu,3 Caroline S. Hill,2 and Alex N. Bullock1,* 1Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom 2Laboratory of Developmental Signalling, Cancer Research UK London Research Institute, London, United Kingdom 3Department of Medicine Cardiovascular Division, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America 4Laboratory for Drug Discovery in Neurodegeneration, Brigham and Women’s Hospital and Harvard Medical School, Cambridge, Massachusetts, United States of America 5Botnar Research Centre, University of Oxford, Oxford, United Kingdom

SUNY Upstate Medical University, United States of America

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This work is ineligible for copyright and therefore in the public domain because it consists entirely of information that is common property and contains no original authorship.

(standard chemical structure)

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current18:20, 5 January 2014Thumbnail for version as of 18:20, 5 January 2014179 × 228 (15 KB)Wnt (talk | contribs)User created page with UploadWizard

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