File:LDLR Binding Module5 1ajj.PNG
LDLR_Binding_Module5_1ajj.PNG (630 × 599 pixels, file size: 43 KB, MIME type: image/png)
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editDescriptionLDLR Binding Module5 1ajj.PNG | The structure of ligand-binding repeat 5 (LR5) of the en:LDL Receptor, which contains a calcium ion (grey) coordinated by acidic residues that lie at the carboxy-terminal end of the domain, and a sulfate ion (yellow and red spheres). Mutations affecting the coordination of the calcium or otherwise alter the structure of this domain are found in patients with the disease familial hypercholesterolaemia. |
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Source | self-made using King v.2.12 (http://kinemage.biochem.duke.edu) using Protein Data Bank coordinates at http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ajj |
Author | InfoCan |
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I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law. |
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current | 17:03, 10 January 2008 | 630 × 599 (43 KB) | InfoCan (talk | contribs) | {{Information |Description=The structure of ligand-binding repeat 5 (LR5) of the en:LDL Receptor, which contains a calcium ion (grey) coordinated by acidic residues that lie at the carboxy-terminal end of the domain, and a sulfate ion (yellow and red |
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