File:LMNA protein (1ifr) mutation R527L PMID 22549407 surface and cartoon.png
![File:LMNA protein (1ifr) mutation R527L PMID 22549407 surface and cartoon.png](https://upload.wikimedia.org/wikipedia/commons/thumb/4/41/LMNA_protein_%281ifr%29_mutation_R527L_PMID_22549407_surface_and_cartoon.png/499px-LMNA_protein_%281ifr%29_mutation_R527L_PMID_22549407_surface_and_cartoon.png?20141024154127)
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editDescriptionLMNA protein (1ifr) mutation R527L PMID 22549407 surface and cartoon.png |
English: Wild type (left) and mutated (right) form of lamin A (LMNA, pdb id: 1IFR). Normally, arginine 527 (blue) forms salt bridge with glutamate 537 (magenta), but R527L substitution results in braking this interaction (leucine is too short to reach glutamate). Models are presented as surface (upper) and in cartoon representation (down). |
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Date | 24 October 2014 (original upload date) | ||
Source | Own work; Draft figure for PMID 22549407. | ||
Author | Lukasz Kozlowski | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 15:41, 24 October 2014 | ![]() | 586 × 704 (1.18 MB) | LPKozlowski (talk | contribs) | Wild type (left) and mutated (right) form of lamin A (LMNA, pdb id: 1IFR). Normally, arginine 527 (blue) forms salt bridge with glutamate 537 (magenta), but R527L substitution results in braking this interaction (leucine is to short to reach glutamate... |
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File change date and time | 15:33, 24 October 2014 |