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English: Pyronin Y (PY) analysis of LT-HSCs (A: LSK-SP and LSK-CD34− cells) and ST-HSCs (B: LSK-non-SP and LSK-CD34+ cells). PY staining, which stains single RNA and DNA, is an assay for discrimination of G0 phase of cell cycle. PYlow/− and PY+ cells are in G0 and G1 of the cell cycle, respectively. Most of LSK-SP and LSK-CD34- cells are PYlow/−, suggesting that LT-HSCs are in G0.
Date Published July 11, 2008.
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StemBook Figure 1 LT-HSCs are in the quiescent state.

  • Arai, F. and Suda, T., Quiescent stem cells in the niche (July 11, 2008), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.6.1, http://www.stembook.org.
Author Arai, F. and Suda, T., Quiescent stem cells in the niche (July 11, 2008), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.6.1, http://www.stembook.org.
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