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File:Location of multipotent stem cells with neurogenic potential in facial and trunk skin..jpg

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English: In the facial skin (left panel), neural crest-derived structures (shown in blue) harbor NCSCs located in the bulge, dermal sheath (DS), and dermal papilla (DP). NCSCs associated with the glial lineage are associated with nerve endings. Melanocyte stem cells in the bulge (MSCs), melanoblasts (Mb), and melanocytes (M) are as well of neural crest origin. In the facial skin, skin-derived precursors (SKPs) located in the dermal papilla originate from the neural crest. Moreover, note that other structures such as the capsula and ringwulst (not labeled in the scheme) contain neural crest-derived cells with sphere-forming potential.In the trunk skin (right panel), NCSCs are found both in the bulge containing MSCs and associated with nerve endings. Melanoblasts (Mb) and melanocytes (M) are of neural crest origin as well. Note that dermal papilla (DP) does not derive from the neural crest in the trunk skin. SKPs (shown in green) reside in the DP and can be isolated by means of their GFP expression in Sox2-GFP mice.
Date NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
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StemBook Figure 3 Location of multipotent stem cells with neurogenic potential in facial and trunk skin.

  • Shakhova, O., and Sommer, L., Neural crest-derived stem cells (May 4, 2010), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.51.1, http://www.stembook.org.
Author Shakhova, O., and Sommer, L., Neural crest-derived stem cells (May 4, 2010), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.51.1, http://www.stembook.org.
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