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File:Lymph node - Atypical mycobacterial infection (MAI) (7342847924).jpg

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Description Impairment of cell-mediated immunity with abnormal macrophage function may interfere with the ability of macrophages to inactivate and kill bacteria and/or eliminate bacterial degradation products. Instead of organizing themselves into compact discrete aggregates to form granulomas, the bacteria-filled macrophages proliferate diffusely forming large sheets of cells. This is what occurs in atypical mycobacterial infections in immunocompromised individuals. The inflammatory response in immunocompetent individuals to atypical mycobacterial infection is usually granulomatous. In this image almost all of the lymphoid tissue is replaced by large histiocytes admixed with a small number of other inflammatory cells. A single granuloma is present in the right lower quadrant.
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Lymph node - Atypical mycobacterial infection (MAI)

Author Yale Rosen from USA

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This image, originally posted to Flickr, was reviewed on 12 February 2014 by the administrator or reviewer File Upload Bot (Magnus Manske), who confirmed that it was available on Flickr under the stated license on that date.

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current08:53, 12 February 2014Thumbnail for version as of 08:53, 12 February 20141,050 × 694 (213 KB)File Upload Bot (Magnus Manske) (talk | contribs)Transferred from Flickr by User:CFCF

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