English: Ensemble fragment mapping results highlight three non-nucleotide binding sites. Representative Ras crystal structure conformers (gray protein cartoon) are shown along with the nucleotide-binding site (red molecular surface representation) and new potential binding sites p1, p2 and p3 (in pink, green and blue molecular surface representations respectively). Also shown is an average Ras conformer where relative chain thickness and color scale (red: high, gray: low) represent residue wise probe occupancy values (see text for details).