File:Origin of fibroblasts during fibrosis and its reversal by BMP-7.jpg
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editDescriptionOrigin of fibroblasts during fibrosis and its reversal by BMP-7.jpg |
Figure 4. Origin of fibroblasts during fibrosis and its reversal by BMP-7. |
Date | |
Source | https://www.jci.org/articles/view/39104 The basics of epithelial-mesenchymal transition J Clin Invest. 2009;119(6):1420-1428. https://doi.org/10.1172/JCI39104. |
Author | Raghu Kalluri, Robert A. Weinberg |
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Open access https://www.jci.org/kiosks/terms The JCI is a Gold Open Access journal in which all content is freely available wthout charge to the user or their institution. Effective with the January 4, 2022, issue, all content is published with a Creative Commons Attribution License (CC BY 4.0).
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current | 00:30, 20 May 2024 | 1,709 × 864 (796 KB) | Rasbak (talk | contribs) | {{Information |description=Figure 4. Origin of fibroblasts during fibrosis and its reversal by BMP-7.<br> (A) Different sources of fibroblasts in organ fibrosis. Four possible mechanisms are depicted. One study suggests that about 12% of fibroblasts are from bone marrow, about 30% can arise via local EMT involving tubular epithelial cells under inflammatory stress, and about 35% are from EndMT (1). The remaining percentage likely emerge via proliferation of the resident fibroblasts and other... |
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