File:Protein stability graph.png
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English: The effect of stability on protein fitness. Intermediate levels of stability are optimal for proteins. Selection pressure on the left had side of the curve increases stability to avoid aggregation, degradation and unfolding. Selection on the right hand side reduces stability in order to maintain activity and avoid uncontrolled toxic accumulation of protein. Genetic drift in the central region reduces stability down to the minimum viable threshold as random mutations (on average) erode stability. |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 10:44, 21 January 2015 | | 970 × 510 (22 KB) | Evolution and evolvability (talk | contribs) | User created page with UploadWizard |
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